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1 15 15 11 3a
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a9 RadioBiology and Imaging Program (RBI) Retreat 2025

19 19 19 31 19 65 19 19 49 31 31 19 19 19 19 19 45
43
Date/Time:
2 42

Wednesday, May 14, 2025, 8:00am - 4:30pm

2 25
Location:
2 34

Rubenstein Auditorium and Commons
30 Smilow Center for Translational Research
1f 3400 Civic Center Blvd.
25 Philadelphia, PA 19104

2 2c
Keynote Speaker:
2 35

Peter L. Choyke, MD, FACR
37 Chief Molecular Imaging Branch
33 Center for Cancer Research
30 National Cancer Institute

2 7a

2 f

 

1f
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5 32

Schedule

5 5 1 1a
30
8:00 AM
5 26
47

Registration and Breakfast

9 b
5 7
1 1a
30
8:30 AM
5 26
2c

5a

Welcome and Overview of the RBI Program
2f Katherine Nathanson, MD
2c Deputy Director, Abramson Cancer Center

7
b
5 7
1 1a
29
5 26
71

Session 1: Cutting-Edge Clinical Trial in Radiation Therapy & Imaging

9 b
5 7
1 1a
30
8:40 AM
5 26
2c

d5

Liver Directed Therapy for Neuroendocrine Tumors
2a Michael Soulen, MD
1c Department of Radiology

7
b
5 7
1 1a
30
9:00 AM
5 26
2c

117

Proton FLASH Radiotherapy: From preclinical studies in mice and canines to human clinical trials
2c Costas Koumenis, PhD
25 Department of Radiation Oncology

7
b
5 7
1 1a
2f
9:20AM
5 26
2c

dd

Clinical Trials in Nuclear Medicine Imaging and Therapy
2b Michael Farwell, MD
1c Department of Radiology

7
b
5 7
1 1a
30
9:40 AM
5 26
2c

52

Introduction of Keynote Speaker
2d Terence Gade, MD, PhD
1c Department of Radiology

7
b
5 7
1 1a
30
9:45 AM
5 26
2c

48

Keynote Presentation:
65 Intercepting the Trajectory of Cancer: The Role of Advanced Molecular Imaging
29 Peter L. Choyke, MD, FACR
47 Chief, Molecular Imaging Branch of the National Cancer Institute
22 National Institutes of Health

7
b
5 7
1 1a
31
10:45 AM
5 26
2c

49

Break and Poster Viewing

7
b
5 7
1 1a
29
5 26
87

Session 2: Radiation and Imaging Reimagined: Technologies Shaping the Interception Frontier

9 b
5 7
1 1a
31
11:00 AM
5 26
2c

e6

Photon-Counting CT: Unlocking New Opportunities in Diagnostic Imaging
28 Peter Noël, PhD
1c Department of Radiology

7
b
5 7
1 1a
31
11:20 AM
5 26
2c

94

Intelligent Plans, Evolving Biology: AI-Driven Radiotherapy at the Interception Frontier
28 Rafe McBeth, PhD
25 Department of Radiation Oncology

7
b
5 7
1 1a
31
11:40 AM
5 26
2c

12c

Chemical Tools for Alpha Radiopharmaceutical Therapy: Investigating Questions in Radiobiology and Impact on Drug Development
2e Mark Sellmyer, MD, PhD
1c Department of Radiology

7
b
5 7
1 1a
31
12:00 PM
5 26
2c

d3

Translational Nanomaterials for Imaging and Radiotherapy
29 David Cormode, MD
1c Department of Radiology

7
b
5 7
1 1a
31
12:20 PM
5 26
2c

49

Lunch and Poster Viewing

7
b
5 7
1 1a
29
5 26
85

Session 3: Decoding Biology to Direct the Future of Precision Radiation and Theranostics

9 b
5 7
1 1a
30
1:20 PM
5 26
2c

f6

Rapid adaptive translation in response to therapy-induced stress in prostate cancer
29 Crystal Conn, PhD
25 Department of Radiation Oncology

7
b
5 7
1 1a
30
1:40 PM
5 26
2c

14c

Enhancing Outcomes in Medically Inoperable Early-Stage NSCLC with Gut-Targeted Antibiotics and Stereotactic Body Radiotherapy: Results from a Randomized Pilot Study
2e Andrea Facciabene, PhD
25 Department of Radiation Oncology

7
b
5 7
1 1a
30
2:00 PM
5 26
2c

ef

Targeting NIR Fluorescent Dyes for Intraoperative Lung Cancer Visualization
2a Jim Delikatny, PhD
1c Department of Radiology

7
b
5 7
1 1a
30
2:20 PM
5 26
2c

f0

Improving cardiac sparing in lung cancer with FLASH proton radiotherapy
2f Ioannis Verginadis, PhD
25 Department of Radiation Oncology

7
b
5 7
1 1a
30
2:40 PM
5 26
2c

4f

Break and Poster Viewing 

7
b
5 7
1 1a
29
5 26
80

Session 4: Mentored Member Presentations - A Bright Future in Radiobiology & Imaging

9 b
5 7
1 1a
30
3:00 PM
5 26
2c

134

Distinct metabolic phenotype renders β-catenin mutant hepatocellular carcinoma susceptible to treatment-induced ischemia
2e Kelley Weinfurtner, MD
1b Department of Medicine

7
b
5 7
1 1a
30
3:10 PM
5 26
2c

109

Dual-Tracer Multiparametric Imaging with a Long-Axial Field-of-View PET to Better Characterize Cancer
29 Austin Pantel, MD
1c Department of Radiology

7
b
5 7
1 1a
30
3:20 PM
5 26
2c

f4

Hyperpolarized Imaging of BCAT1 for Targeted Hepatocellular Carcinoma Therapy
31 David Tischfield, MD, PhD
1c Department of Radiology

7
b
5 7
1 1a
29
5 26
40

Session 5: Abstracts

37

 

1 e

 

7
b
5 7
1 1a
30
3:30 PM
5 26
2c

10e

FLASH Radiotherapy and an Injectable Drug Delivery Hydrogel as a Combination Treatment for Glioblastoma
2b Kathleen Villasenor
21 Department of Bioengineering

7
b
5 7
1 1a
30
3:40 PM
5 26
2c

fc

Radiation-Induced Neoantigens as Targets for AND-Gate CAR T-Cell Therapy in PDAC
32 Nektarios Kostopoulos, PhD
25 Department of Radiation Oncology

7
b
5 7
1 1a
30
3:50 PM
5 26
2c

109

Chronic Radiation Toxicities Are Attenuated Following Fractionated Proton FLASH Radiotherapy
33 Anastasia Velalopoulou, PhD
25 Department of Radiation Oncology

7
b
5 7
1 1a
30
4:00 PM
5 26
2c

125

Flash proton re-irradiation with hypofractionation mitigates radiation-induced toxicity of the head and neck tissues in mice
2f Priyanka Chowdhury, PhD
27 Department of Radiation Oncology
b  

7
b
5 7
1 1a
30
4:10 PM
5 26
2c

f1

An Analytical Physics-Guided Standardization Approach for Radiomics Analysis in CT
20 Huay Din
27 Department of Bioengineering 

7
b
5 7
1 1a
30
4:20 PM
5 26
2c

40

Closing Remarks

7
b
5 3a

Posters

1 1a
29
5 26
2c

f3
PixelPrint4D: A 3D Printing Method for Fabricating Patient-specific Deformable Pulmonary CT Phantoms 2b

Jessica Im; Department of Radiology

1 be

Dual-contrast Imaging of Gadolinium and Iodine using K-edge Imaging in PCCT
32 Martin Rybertt; Department of Radiology 

1 e5

Targeting STAT3 Remodels the Tumor Microenvironment and Enhances Radiotherapy Response in Pancreatic Cancer
3c Ioannis Paraskevaidis; Department of Radiation Oncology

1 df

Unraveling Disease Heterogeneity: Generative Adversarial Network based Normative Modeling
32 Spandana Chintapalli; Department of Radiology

1 b8

Development of FLASH-CAR radioimmunotherapy for pediatric brain tumor
3e MD Naushaud Akhtar, PhD; Department of Radiation Oncology

1 cd

Heme Oxygenase Inducers with Anti-PD1 Antibody for Tumor Control of Murine Pleural Mesothelioma
30 Lyna Dinh; Department of Radiation Oncology

1 fe

Targeted Administration of Lactate Dehydrogenase Inhibitor during Transarterial Embolization of Target Hepatocellular Carcinomas in a Rat Model
28 Ryan Baron; Department of Radiology

1 f1

Response Assesment to Immune Checkpoint Inhibitors in Recurrent Glioblastomas using Multiparametric MRI based Prediction Model
38 Sanjeev Chawla, PhD, DABMP; Department of Radiology

1 c3

A Genetically Encoded Hyperpolarized MRI Reporter for in Vivo Cell Tracking 
30 Molly Sheehan, PhD; Department of Radiology

1 c4

Strategies for Improving Complete Tumor Resection in Glioblastoma Multiforme (GBM)
30 Jennifer Ferd; Department of Bioengineering

1 ea

Longitudinal Imaging and Funcitonal Characterization of Liver Regeneration and Humanization in a Translational SRG Rat Model
27 Yohan Kim, Department of Radiology

1 e0

Metabolic imaging differentiates ischemia reperfusion injury severity in a translational mouse model
39 Shurik "Alexander" Zavriyev, Department of Radiology

7
b
5 7
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1 1 5c
Past RBI Retreats:
2 6 7
1 1 19 1b
11 15 11 15 25 11 11 11 18
9 13