Welcome to the Department of Radiation Oncology

Message from James M. Metz, MD — Chairman

Penn Radiation Oncology is dedicated to a three-part mission of excellence in patient care, basic and translational research, and the education of residents and students. We are committed to delivering excellence in every area and as such we steadfastly believe that "Excellence is Standard."

Penn Radiation Oncology is one of the most comprehensive radiation oncology programs in the world. The outstanding faculty and staff, combined with Penn’s extensive collection of advanced technology, gives patients access to nearly every treatment option available for their cancer. The broad range of radiation treatments available include proton therapy, intensity-modulated radiation therapy (IMRT), high-dose rate (HDR) and low-dose rate brachytherapy, partial breast irradiation, stereotactic radiosurgery (SRS), and Gamma Knife radiation. With the Abramson Cancer Center of the University of Pennsylvania, Penn Radiation Oncology provides patient care at the Ruth and Raymond Perelman Center for Advanced Medicine and seven community-based sites.

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Register Today for the 9th Annual Penn Proton Therapy Course



$999 + Taxes/Fees
($1,500 + taxes/fees after November 1st)


$499 + Taxes/Fees
($550 + taxes/fees after November 1st)

This course is being submitted for CAMPEP, ASRT, MDCB and CNE credits

banner for annual proton therapy course



  • FLASH Proton Therapy: Uncovering the Optimal Delivery Technique Thursday, July 28, 2022

    FLASH radiotherapy, which delivers therapeutic radiation at ultrahigh dose rates and offers the potential to vastly reduce normal tissue toxicity while maintaining anti-tumor activity, was the topic of a Best-in-Physics presentation at the American Association of Physicists in Medicine Annual Meeting. Eric Diffenderfer, MD, an assistant professor of Radiation Oncology, presented and compared four FLASH proton delivery techniques.

    Physics World

  • American Society for Radiation Oncology Awards Fellow Designations Tuesday, July 19, 2022

    The American Society for Radiation Oncology (ASTRO) fellow designation honors individuals who made significant contributions to the society and radiation oncology through research, patient care, education, or service to the field. Only 421 of ASTRO’s 10,000-plus members around the world have received this designation since 2006. Alexander Lin, MD, vice chair of Faculty Affairs and medical director of the Roberts Proton Therapy Center in the department of Radiation Oncology, received the honor this year 

  • Potential Target for Future Cancer Therapies Found in a Stress Protein Monday, June 13, 2022

    A stress protein that is overactive in many types of tumor cells also has a key role in tumor-supporting cells called fibroblasts, and may be a good target for future cancer treatments, suggests a study published in Nature Cell Biology. According to senior author Constantinos Koumenis, PhD, the Richard H. Chamberlain Professor of Research Oncology in the department of Radiation Oncology, “Every tumor we’ve looked at upregulates ATF4 and that inhibiting ATF4 could work against many types of cancer, which we are now actively pursuing.”

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