Clinical Research at Penn Medicine Radiation Oncology

Mission Statement

The goal of clinical and translational research in the department of Radiation Oncology at the University of Pennsylvania is to develop novel, more effective, treatment regimens/paradigms for cancer based on cutting edge scientific discoveries, leveraging particular Penn strengths. To that end, we conduct pilot, phase 1 and phase 2 clinical trials. Promising new approaches are then presented to national cooperative groups to be validated in phase 3 trials.

Our research is focused on 5 themes:

• Personalized medicine
• Immunology, immunotherapy and radiation
• Tumor microenvironment, and its interaction with radiation and PDT
• Radiation Response Modifiers
• Novel Technologies (including Protons and FLASH research)

Faculty Leadership

• Costas Koumenis, Ph.D., Vice Chair of Research and Richard H. Chamberlain Professor
• John Plastaras, M.D., Ph.D., Vice Chair of Clinical Research and Professor
• Edgar Ben-Josef, M.D., Vice Chair of Translational Research and Eli Glatstein Professor

Research Intake Forms

Radiation Oncology Nursing Service Request	Radiation Oncology Clinical Trials Resource Request
https://redcap.med.upenn.edu/surveys/?s=HKLWP4AHJEJJK7H7	https://redcap.med.upenn.edu/surveys/?s=ETDP74WMECJFT4LN

For All Clinical Research General Inquiries/ Requests:  

Please email:  radonc_cr@pennmedicine.upenn.edu

Tumor Site Teams

• Gastrointestinal Cancers
• Thoracic Cancers
• Breast and Gynecologic Cancers
• Central Nervous System Cancers
• Genitourinary Cancers
• Head and Neck Cancers
• Hematological Disease

Protocols

• Sharepoint List of Clinical Protocols (UPHS login required)