Department of Radiation Oncology Annual Research Retreat Friday, October 14, 2016

Location:

Arthur H. Rubenstein Auditorium
Smilow Center for Translational Research 
3400 Civic Center Blvd., Philadelphia PA 19104

Schedule:

Please click on titles to view abstracts Or click here for all abstracts.

7:00 - 7:15am POSTER SETUP
7:15 - 7:55am CONTINENTAL BREAKFAST AND POSTER VIEWING
7:55am RETREAT COMMENCES
7:55 - 8:00am

Introductory Comments by Dr. Costas Koumenis
Professor and Vice-Chair of Research, Radiation Oncology, Co-Leader of the Radiation Biology and Imaging Program, Abramson Cancer Center
8:00 - 8:15am "Exosomes from the tumor microenvironment promote breast cancer progression and therapy resistance"
BARZIN NABET
8:15 - 8:30am " A novel mouse model to study image-guided, radiation-induced intestinal injury and preclinical screening of radioprotectors"
IOANNIS (JOHN) VERGINADIS
8:30 - 8:45am " Temporal DNA-PK activation drives genomic instability and radioresistance in glioma stem cells"
YI FAN
8:45 - 9:00m " A methylimidazolium iodide compound induces DR5 dependent TRAIL synergy and selective activity against cancer stem cells"
SAAD SHEIKH
9:00 - 9:15am " The Exploitation of Tumor Microenvironment for Monitoring Orthotopic Models of Pleural Cancer"
RICHARD DAVIS IV
9:15 - 9:30am " From Big Data to Knowledge: Factors predicting a need for treatment re-planning with proton radiotherapy for lung cancer"
CHING-LING TENG
9:30 - 9:45am " Prompt gamma imaging for in vivo proton range verification of pencil beam scanning proton therapy"
KEVIN TEO

9:45 - 10:15am

 COFFEE BREAK AND POSTER VIEWING
10:15 - 10:30am " Can Equivalent Uniform Dose (EUD)-based optimization lead to dose painting and dose guidance?"
DIMITRIS MIHAILIDIS
10:30 - 10:45am " Intestinal microbiome modulates antitumor immune response and impact RT effectivenes"
ANDREA FACCIABENE
10:45 - 11:00am " Avoiding skin creams just before radiation: Good advice or much ado about nothing?"
BRIAN BAUMANN
11:00 - 11:15am " Androgen Deprivation Therapy and Risk of Dementia"
KEVIN NEAD
11:15 - 11:30am " Dosimetry study of PHOTOFRIN-mediated photodynamic therapy in a mouse tumor model"
ROZHIN PENJWEINI
11:30 - 11:45am "Proton Modulated Arc Therapy for Left-Sided Whole Breast Treatment"
ALEJANDRO CARABE-FERNANDEZ
11:45 - 12:00pm "Impact of Prophylactic Cranial Irradiation on Overall Survival in Extensive-Stage Small Cell Lung Cancer: A Propensity Score Matched Analysis"
SONAM SHARMA
12:00 - 1:00pm LUNCH AND POSTER VIEWING
1:00 - 1:10pm "Overview of Penn Radiation Oncology Proton Research Room"
STEVE TUTTLE
1:10 - 1:20pm "Overview of Penn Radiation Oncology Clinical Research"
KAYSEE BAKER
1:20 - 2:20pm

KEYNOTE LECTURE
"Mitigating Radiation Fibrosis with Adipose-Derived Stromal Cells”
Fei-Fei Liu, MD, FRCPC
Professor and Chair of Radiation Oncology, University of Toronto
2:20 - 2:30pm AWARDING OF TOP 2 POSTERS AND BEST ORAL PRESENTATION BY TRAINEES
2:30pm

Closing Comments by Dr. James M. Metz
Henry K. Pancoast Professor and Chair of Radiation Oncology
2:40pm Adjorn

List of Poster Presentations:

  1. "A Tumor Mitochondria Vaccine Protects against Experimental Renal Cell Carcinoma"
    Stefano Pierini
     
  2. "Liposome-encapsulated Doxorubicin is a promising adjuvant to increase the efficacy of mTERT DNA-vaccine"
    Mireia Uribe-Herranz
     
  3. "Target Wnt/Beta-catenin to de-transform tumor vasculature and block glioma progression"
    Menggui Huang 
     
  4. "Glioblastoma-derived circulating tumor cells are cancer stem cell-like cells"
    Tian-run Liu
     
  5. "Role of IL-6 in macrophage-mediated glioma immunity"
    Qirui Wang
     
  6. "Toward Detection of Circulating Tumor Cells from Non-Small Cell Lung Cancer Patients: Validating a Digital PCR-Based Approach"
    Rodrigo Gier
     
  7. "Genome-wide transcriptome analysis identifies a spliced isoform of EIF2B5 which represses translation under hypoxic stress"
    Lauren Brady
     
  8. " Identifying novel regulators of UPR by utilizing genome-scale CRISPR-Cas9 knockout screens"
    Nektaria M. Leli
     
  9. "Nelfinavir: the physiological mechanisms behind its therapeutic enhancement of radiation"
    Intae Lee     
     
  10. "Tumor Interferon Signaling Regulates a Multigenic Resistance Program to Immune Checkpoint Blockade"
    Joseph Benci
     
  11. "The visible signal responsible for proton therapy dosimetry using bare optical fibers is not Cerenkov radiation"
    Arash Darafsheh
     
  12. "Proton therapy dosimetry by using intrinsic fluorescence of silica fibers"
    Arash Darafsheh
     
  13. "Proton Radiography Using Pencil Beam Scanningand a Novel, Low-Cost Range Telescope"
    Derek Dolney
     
  14. "Comparison of Dosimetric Robustness between Proton Therapy and IMRT Plans Following Tumor Regression for Locally Advanced Non-Small Cell Lung Cancer (NSCLC)"
    Ching-Lin Teng
     
  15. " MediBoost: a Patient Stratification Tool for Interpretable Decision Making"
    Jose Marcio Luna

Please Register by October 11, 2016 at:

https://www.surveymonkey.com/r/6HWBJF9