Robert E. Krisch, MD/PhD

Emeritus Associate Professor CE of Radiation Oncology
Department: Radiation Oncology
Contact Information
Chester County Hospital
701 East Marshall Street
West Chester, PA 19380
Office: 800-789-PENN (7366)
Education
-
BA (Natural Sciences)
University of Pennsylvania, 1956 -
M.D. (Medicine)
Temple University, 1960 -
Ph.D.
University of Pennsylvania, 1964
Selected Publications
- Lee JH, Machtay MM, McKenna MG, Markiewicz DA, Krisch RE, Weinstein GS, Kligerman MM : : Radiotherapy with 6MV photons for early glottic carcinoma: potential impact of extension to the posterior vocal cord. Amer J Otolaryngol 22 : 43-54, 2001
- Ayene SI, Bernhard EJ, McKenna WG, Muschel R, Krisch RE, Koch CJ : DNA as a target in radiation induced apoptosis of myc and myc plus ras transfected rat embryo fibroblasts: a radiation chemistry approach for intact cells. Int. J. Radiat. Biol 76 : 343-354, 2000
- Ayene SI, Koch CJ, Krisch RE : Modification of radiation induced single and double strand breaks by glutathione: Comparison of single and double strand breaks in SV40 DNA. Radiat Res 144 : 1-8, 1998
- Ayene SI, Sullivan M, Krisch RE, Koch CJ : Protein derived radicals as sensitizers of radiation induced single and double strand DNA breaks. Radiat Res 148 : 499-500, 1997
- Krisch RE, Ayene SI, Sullivan M, Koch CJ : A cell-like •OH scavenging environment alters the charge dependence of radiation protection by thiols. Radiat Res 148 : 498-499, 1997
- Ayene SI, Koch CJ, Krisch RE : : Simulation of the cellular oxygen effect with an in vitro model system using double-strand DNA breaks as an endpoint. Radiat Res 146 : 501-509, 1996
- Ayene SI, Koch CJ, Krisch RE : Role of scavenger-derived radicals in the induction of double strand breaks in irradiated DNA. Radiat Res 142 : 133-143, 1995
- Krisch RE, Ayene SI, Koch CJ : Interaction of Thiol and Non-Thiol Scavengers in the Modification of Radiation-Induced DNA Damage. Radiation Damage in DNA: Structure/Function Relationships at Early Times : 383-391, 1995
- Sause WT, Scott C, Krisch R, Rotman M, Sneed PK, Janjan N, Davis L, Curran W, Choi KN, Selim H, Mohiuddin M, Grigsby P : Phase I/II trial of accelerated fractionation in brain metastases RTOG 85-28 Int J Radiat Oncol Biol Phys 26 : 653-657, 1993
- Curran WJ, Scott CB, Horton J, Nelson JS, Weinstein AS, Fischbach AJ, Chang CH, Rotman M, Asbell SO, Krisch RE, Nelson DF : Recursive partitioning analysis of 1,578 on 3 Radiation Therapy Oncology Group (RTOG) malignant glioma trials. J Natl Cancer Inst 85 : 704-710, 1993