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Radiation Biology Training Program

This is a program designed to train radiation biologists who will have knowledge of the molecular, cellular and tissue effects of radiation. 6 predoctoral and 4 postdoctoral trainees per year participate in this program. Training is offered in the radiation biology and associated laboratories of the Division of Oncology Research and the University of Pennsylvania School of Medicine. The program involves formal coursework, a lecture series and a journal club designed for the trainees. The research projects focus on various aspects of the currently funded research areas in the participating laboratories; for research projects, trainees utilize techniques developed in modern biology to perform mechanistically-oriented studies in radiation biology/oncology. The research areas in which the 14 training directors and supervisors are involved are broadly based in cancer research, including molecular mechanisms of carcinogenesis and mutagenesis, molecular and cellular radiation biology, radiation chemistry and biochemistry, DNA repair processes, cancer prevention and radiation oncology. It is expected that graduates of the training program will continue with their research and academic careers in radiation biology and oncology.

Preceptors

Ann R. Kennedy, D.Sc. Project Director; Professor, Department of Radiation Oncology
Cameron J. Koch, Ph.D. Associate Project Director; Professor, Department of Radiation Oncology
Gary D. Kao, M.D., Ph.D. Trainee Coordinator; Professor, Department of Radiation Oncology
Marcello G. Kazanietz, Ph.D.

Director of Recruitment; Professor, Department of Pharmacology

Steven H. Hahn, M.D. Henry P. Pancoast Professor, Chairman of Radiation Oncology

Theresa M. Busch, Ph.D

Assistant Professor, Department of Radiation Oncology
Wafik S. El-Deiry, M.D., Ph.D. Professor, Department of Hematology-Oncology
Sydney M. Evans, V.M.D. Professor, Department of Radiation Oncology
Jeffrey M. Field, Ph.D. Associate Professor, Department of Pharmacology
Amit Maity, M.D., Ph.D. Associate Professor, Department of Radiation Oncology
Randall N. Pittman, Ph.D. Professor, Department of Pharmacology
Thomas Stamato, Ph.D. Assistant Professor, Wistar Department of Radiation Biology

H and E ZF
Effects of ionizing radiation on the morphology of the
developing central nervous system and eye in zebrafish
embryos --a model system developed throught the Radiation
Biology Training Program.

Left images show H&E-stained sagittal sections of the
cranial structures of representative surviving zebrafish
embryos at 144 hpf after exposure at 4 hpf to 0 (Control ),
10, 20, or 10 Gy with amifostine.
Right images show H&E-stained transverse sections through
the central retina of surviving zebrafish embryos at 144
hpf after exposure at 4 hpf to 0 (Control), 10, or 10 Gy
with amifostine. Insets, representative eyes from
identically treated embryos from a coronal erspective.
[link to PDF (Geiger, et al. Cancer Research, 2006)]

For information about the Radiation Biology Training Program, contact the Program Director (by email: akennedy@mail.med.upenn.edu or telephone: (215) 898-0079 or send your application to the Program Director at the address shown below)

Dr. Ann R. Kennedy
Department of radiation Oncology
University of Pennsylvania School of Medicine
195 John Morgan Building
3620 Hamilton Walk
Philadelphia, PA 19104-6072

Training Program Preceptors
Radiation and Cancer Biology Course

Previous Program Trainees (PDF) (1992-Present)

Radiation Biology Seminar Series 2008 (PDF)

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