Department of Radiation Oncology

EDUCATION

1992-2001

University of Michigan Medical School & Rackham School of Graduate Studies Medical Scientist Training Program, Ann Arbor, MI

M.D. with Distinction in Research awarded June 2001

Ph.D. in Biological Chemistry awarded April 2001

M.S. in Biological Chemistry awarded August 1995

1989-1992

University of Michigan College of Literature, Science, and the Arts, Ann Arbor, MI

B.Sc. in Chemistry with Highest Distinction awarded May 1992

POSTRGRADUATE APPOINTMENTS

2006- Present

University of Pennsylvania, Philadelphia, Pennsylvania Assistant Professor, Department of Radiation Oncology

2002-2006

Memorial Sloan-Kettering Cancer Center, New York, New York Resident, Department of Radiation Oncology

2001-2002

St. Mary’s Medical Center, San Francisco, California Intern, Department of Internal Medicine

LICENSURE AND CERTIFICATION

2006

Pennsylvania State License to Practice as a Medical Physician and Surgeon

2006

California State License to Practice as a Physician and Surgeon

2006

New Jersey State License to Practice Medicine and Surgery

2002

New York State License to Practice Medicine and Surgery

2002

Diplomate of the National Board of Medical Examiners

HONORS AND AWARDS

2005

Educational Travel Grant, 6th Annual Perspectives in Colorectal Cancer; Chicago, Il

2005

Roentgen Resident/Fellow Research Award

2004

Young Oncologist Essay Award, American Radium Society

2004

Best of ASCO Travel Fellowship

2002

Preliminary Intern of the Year, St. Mary’s Medical Center

1998

Travel Fellowship, Society for Leukocyte Biology

1994-1995

Fellowship, Pharmacological Sciences Training Program, Departments of Biological Chemistry and Pharmacology, University of Michigan Medical School

1992-2001

Fellowship, Medical Scientist Training Program, University of Michigan Medical School

1990

Fellowship, Summer School in Nuclear Chemistry, Brookhaven National Laboratory

1989

Finalist, National Merit Scholarship Program

LABORATORY RESEARCH EXPERIENCE

1994-1998

1994-1998 University of Michigan - Department of Biological Chemistry
Signaling mechanisms regulating actin cytoskeletal function in hematopoietic lineages

1993

University of Michigan - Department of Biological Chemistry
Activation and regulation of the pentose phosphate shunt in mammalian cells

1990-1992

1990-1992 University of Michigan Medical School - Department of Nuclear Medicine
Identifying predictive factors for aromatic nucleophilic substitution with [18F]fluoride ion

CLINICAL RESEARCH EXPERIENCE

2002-Present

Memorial Sloan-Kettering Cancer Center - Department of Radiation Oncology

Predicting the need for neck dissection in patients with locally advanced head and neck cancer treated with chemoradiation (current project)

Functional and oncologic outcome of sphincter preservation in distal cT2N0 rectal cancers treated with preoperative external beam radiotherapy

Long-term followup of a Phase I/II sphincter preservation protocol for patients with distal T2/T3 rectal adenocarcinoma

Impact of dose escalation on outcomes in patients with locally advanced non-small cell lung cancer

Use of PET/CT registration to determine target volumes in lung cancer

1990

1990 Brookhaven National Laboratory - Radiotracer Chemistry and Neuroimaging
Program

Use of positron emission tomography (PET) for neurologic imaging

1. R. Rengan, P. Paty, W.D. Wong, J. Guillem, M. Weiser, L. Temple, L. Saltz, and B.D. Minsky. 10 year results of preoperative radiation followed by sphincter preservation for rectal cancer: Increased local failure rates in non-responders. Clinical Colorectal Cancer 5(6): 413-421 (2006)

2. R. Rengan, D. Pfister, N. Lee, D. Kraus, J. Shah, A. Shaha, L. Ben Porat, and M. Zelefsky. Long-term neck control rates after complete response to chemoradiation in patients with advanced head and neck cancer. (manuscript in submission)

3. R. Rengan, P. Paty, W.D. Wong, J. Guillem, M. Weiser, L. Temple, L. Saltz, and B.D. Minsky. Distal cT2N0 rectal cancer - is there an alternative to abdominoperineal resection? JCO 23(22): 4905-4912 (2005)

4. J.L. Fox, R. Rengan, W.P. O’Meara, E. Yorke, Y. Erdi, S. Nehmeh, S. Leibel, and K.E. Rosenzweig. Does the registration of FDG-PET and planning CT images decrease inter- and intra-observer variation in delineating tumor volumes for non-small cell lung cancer (NSCLC)? IJROBP 62(1):70-5 (2005)

5. R. Rengan, K.E. Rosenzweig, E.S. Venkatraman, L.A. Koutcher, J.L. Fox, R. Nayak, H. Amols, E. Yorke, A. Jackson, C.C. Ling, and S.A. Leibel. Improved local control with higher doses of radiation in large-volume stage III non-small cell lung cancer. IJROBP 60(3): 741-747 (2004)

6. R. Rengan and H.D. Ochs. Molecular biology of the Wiskott-Aldrich Syndrome. Reviews in Immunogenetics 2: 243-255 (2000)

7. R. Rengan, H.D. Ochs, L.I. Sweet, M.L. Keil, W.T. Gunning, N.A. Lachant, L.A. Boxer, and G.M. Omann. Actin cytoskeletal function is spared, but apoptosis is increased in WAS patient hematopoietic cells. Blood 95: 1282-1292 (2000)

8. R. Rengan and G.M. Omann. Regulation of oscillations in filamentous actin content in polymorphonuclear leukocytes stimulated with leukotriene B4 and platelet activating factor. Biochemical and Biophysical Research Communications 262: 479-486 (1999)

9. R. Rengan. Signaling actin polymerization responses in hematopoietic cells. Doctoral Dissertation, University of Michigan Medical School (1998)

10. G.M. Omann, R. Rengan, J.F. Hoffman, and J.J. Linderman. Rapid oscillations of actin polymerization/ depolymerization in polymorphonuclear leukocytes stimulated by leukotriene B4 and platelet activating factor. Journal of Immunology 155(11): 5375 (1995)

11. R. Rengan, P.K. Chakraborty, and M.R. Kilbourn. Can we predict reactivity for aromatic nucleophilic substitution with [18F]fluoride ion? Journal of Labelled Compounds and Radiopharmaceuticals 33:563-572 (1992)